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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING) |
| Enrichment Score (ES) | -0.5998956 |
| Normalized Enrichment Score (NES) | -1.4498577 |
| Nominal p-value | 0.044397462 |
| FDR q-value | 0.635611 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMC1 | 6350538 | 749 | 1.196 | 0.0145 | No | ||
| 2 | PSMA7 | 2230131 | 1110 | 0.981 | 0.0401 | No | ||
| 3 | PSMA4 | 4560427 | 1353 | 0.847 | 0.0659 | No | ||
| 4 | PSMD2 | 4670706 5050364 | 1569 | 0.747 | 0.0886 | No | ||
| 5 | PSMB3 | 4280594 | 2122 | 0.524 | 0.0830 | No | ||
| 6 | SOCS1 | 730139 | 2767 | 0.345 | 0.0641 | No | ||
| 7 | JAK1 | 5910746 | 3521 | 0.209 | 0.0332 | No | ||
| 8 | PSMA6 | 50609 | 5241 | 0.083 | -0.0555 | No | ||
| 9 | PSMA1 | 380059 2760195 | 7365 | 0.030 | -0.1683 | No | ||
| 10 | PSMA3 | 5900047 7040161 | 7567 | 0.026 | -0.1779 | No | ||
| 11 | STAT5B | 6200026 | 11319 | -0.029 | -0.3784 | No | ||
| 12 | JAK2 | 3780528 6100692 6550577 | 12300 | -0.050 | -0.4288 | No | ||
| 13 | PSMB6 | 2690711 | 12943 | -0.068 | -0.4603 | No | ||
| 14 | PSMB1 | 2940402 | 14372 | -0.140 | -0.5307 | No | ||
| 15 | PSMA5 | 5390537 | 15315 | -0.238 | -0.5704 | No | ||
| 16 | PSMB2 | 940035 4210324 | 15589 | -0.284 | -0.5721 | No | ||
| 17 | PSMB4 | 520402 | 16107 | -0.384 | -0.5823 | Yes | ||
| 18 | PSMB8 | 2850707 | 16254 | -0.424 | -0.5707 | Yes | ||
| 19 | STAT3 | 460040 3710341 | 16445 | -0.480 | -0.5589 | Yes | ||
| 20 | STAT1 | 6510204 6590553 | 17138 | -0.723 | -0.5630 | Yes | ||
| 21 | PSMB7 | 5570088 5890647 | 17213 | -0.754 | -0.5325 | Yes | ||
| 22 | PSMB5 | 6290242 | 17227 | -0.759 | -0.4984 | Yes | ||
| 23 | STAT2 | 3780519 | 17239 | -0.763 | -0.4640 | Yes | ||
| 24 | STAT4 | 1660373 3130019 | 17295 | -0.784 | -0.4310 | Yes | ||
| 25 | STAT5A | 2680458 | 17538 | -0.913 | -0.4021 | Yes | ||
| 26 | PSMA2 | 6510093 | 17803 | -1.057 | -0.3679 | Yes | ||
| 27 | JAK3 | 70347 3290008 | 18429 | -1.829 | -0.3176 | Yes | ||
| 28 | PSMB9 | 6980471 | 18481 | -2.011 | -0.2282 | Yes | ||
| 29 | TYK2 | 1660465 1740736 | 18564 | -2.459 | -0.1198 | Yes | ||
| 30 | PSMB10 | 630504 6510039 | 18586 | -2.673 | 0.0016 | Yes |
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